The Supreme Court is set to hear arguments on Wednesday in just its second major transgender rights case, a challenge to a Tennessee law that bans gender-affirming care for minors.The nation’s top court will be weighing whether Tennessee’s law violates the equal protection clause of the 14th Amendment,

There was a clarifying moment late in Wednesday’s two-and-a-half-hour-long oral argument in United States v. Skrmetti, a history-making challenge to Tennessee’s ban on gender-affirming care for minors.

The ruling could set a precedent for several challenges to state laws regarding sports participation, bathroom use and health care for adults.