SportsLine's model has simulated San Francisco vs. Buffalo on Sunday Night Football 10,000 times and revealed its SNF picks ...

Following their high-profile victory over the AFC-leading Chiefs, the Bills went off the NFL radar for their much-needed Week ...

And if the Chiefs game is any indication of what could be, the Bills' interior defensive line has a chance to be as equally ...

Pop superstar Taylor Swift is spending Black Friday amid a sea of red to watch her boyfriend, Travis Kelce, and the rest of ...

The Bills are activating Matt Milano (biceps) off injured reserve and the linebacker will make his long-awaited return on ...

The results were ugly for the San Francisco 49ers last week against the Green Bay Packers without starting quarterback Brock ...

Analyzing Sunday’s San Francisco 49ers at Buffalo Bills odds and lines, with expert NFL picks and predictions.

The #Bills have activated Pro Bowl LB Matt Milano off Injured Reserve and he’ll play on Sunday against the #49ers for the ...

The Buffalo Bills played the Kansas City Chiefs in their last game before heading into the bye week. They pulled off the ...

Buffalo (9-2) brings a six-game winning streak into a matchup with San Francisco (5-6) on Sunday, December 1, 2024 at ...

Running back Christian McCaffrey says the San Francisco 49ers are “hungry” to make a playoff push even with the defending NFC ...

One thing does not change, though. The defending NFC champion 49ers are 5-6 and they need to get on a heater - which will be ...