San Francisco 49ers quarterback Brock Purdy missed last week's game against the Green Bay Packers. Will he play against the ...

The Buffalo Bills will play the San Francisco 49ers at home at Highmark Stadium on "Sunday Night Football" in Week 13. The ...

Here are the full injury reports for the Buffalo Bills and San Francisco 49ers ahead of their Week 13 matchup at Highmark ...

While the 49ers look like an easy opponent, San Francisco's health could be a major factor in the game, warns one NFL expert.

See who's in and who's out for the Week 13 matchup between the Buffalo Bills and San Francisco 49ers on December 1, 2024.

The AFC East-leading Buffalo Bills return from their bye week to host the inconsistent San Francisco 49ers on Sunday night.

Buffalo Bills coach Sean McDermott looked and sounded refreshed as he and his team returned from its bye week.

The Buffalo Bills will have to wait and see what happens with tight end Dalton Kincaid as his status for this week is up in ...

The 49ers have revealed their latest injury report from Wednesday’s practice before their Sunday Night Football tilt against ...

San Francisco has been up and down all season, but the Super Bowl hangover appears to be happening after the 49ers got ...

NFL Week 13 odds, picks, predictions, TV and streaming information for Sunday Night Football game between the San Francisco ...

The 49ers travel to Buffalo to take on the AFC East-leading Buffalo Bills. Check out our best bet for the game ...