San Francisco 49ers star Deebo Samuel had a blunt reaction when asked about his low numbers to begin this season.

With the Bills (9-2) on the cusp of a fifth straight AFC East division title, the pressure is on Allen and Co. to deliver the ...

The Bills attempt to win seven in a row when they host the 49ers in this Week 13 NFL odds, prediction, and pick.

The Buffalo Bills will play the San Francisco 49ers at home at Highmark Stadium on “Sunday Night Football” in Week 13. The ...

A disciple of hyper-aggressive deceased Philadelphia Eagles defensive coordinator Jim Johnson, McDermott’s defenses share ...

WR Curtis Samuel (vs. 49ers) — Samuel made mincemeat out of the Chiefs in his last game. But with Keon Coleman and Dalton ...

One of the top receivers in the league will be featured when George Kittle and the San Francisco 49ers visit the Buffalo ...

How much weight do you want to put on the frozen-Fish angle? The forecast at Lambeau is 21 degrees, a real feel of 4 with 15 ...

As the NFL season heats up, Week 12 reveals a competitive MVP race. Standouts include Lamar Jackson, Josh Allen, and Patrick ...

Now that the holiday season is in full swing, several Bills players are taking the time to be active in the community. A ...

The 49ers are welcoming Brock Purdy back to practice today after shoulder soreness kept him out of Sunday’s loss at Green Bay.

Simpson carried the ball 29 times against the Lions and set a new NFL record with 273 rushing yards, breaking his own record ...