Former Buffalo Bills defensive end Leonard Floyd spoke about facing his old team on Sunday night with the San Francisco 49ers ...

San Francisco 49ers quarterback Brock Purdy missed last week's game against the Green Bay Packers. Will he play against the ...

The Buffalo Bills might have a chance to clinch the AFC East on Sunday night when they battle the injury-decimated San ...

See who's in and who's out for the Week 13 matchup between the Buffalo Bills and San Francisco 49ers on December 1, 2024.

The 49ers are welcoming Brock Purdy back to practice today after shoulder soreness kept him out of Sunday’s loss at Green Bay.

The 49ers happened to have room at quarterback amid Brock Purdy's injury. Kyle Shanahan revealed if Daniel Jones was a ...

SANTA CLARA — While Brock Purdy resumed practicing through a shoulder issue and Dre Greenlaw made a much-anticipated debut ...

The San Francisco 49ers 2024 Salute to Service nominee, George Kittle, enthusiastically cheered on his high school teammate ...

All six of the NFL teams playing on Thanksgiving will be without critical players. The Chicago Bears will be without center ...

The San Francisco 49ers are reeling and now head to Buffalo for a prime time game. Will they have their starting QB back in ...

Even after the injury, Brock Purdy is set to return as soon as possible, however that might not be the case and the San ...

The banged-up San Francisco 49ers received some positive news on Wednesday. Per ESPN's Nick Wagoner, 49ers head coach Kyle ...